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Cellosaurus HEK293 RPS2 A226Y (CVCL_YD69)

[Text version]

Cell line name HEK293 RPS2 A226Y
Accession CVCL_YD69
Resource Identification Initiative To cite this cell line use: HEK293 RPS2 A226Y (RRID:CVCL_YD69)
Comments Characteristics: Transfected with mutated Rps2 linked to IRES-eGFP.
Transfected with: MGI; MGI:105110; Rps2 (with p.Ala226Tyr).
Transfected with: UniProtKB; P00557; E.coli hygromycin-B 4-O-kinase (hph).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Omics: Deep RNAseq analysis.
Omics: Metabolome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=31637312; DOI=10.1038/s42003-019-0626-9
Shcherbakov D., Teo Y., Boukari H., Cortes-Sanchon A., Mantovani M., Osinnii I., Moore J., Juskeviciene R., Brilkova M., Duscha S., Kumar H.S., Laczko E., Rehrauer H., Westhof E., Akbergenov R., Bottger E.C.
Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis.
Commun. Biol. 2:381-381(2019)

Cross-references
Gene expression databases GEO; GSM3168273
GEO; GSM3168274
GEO; GSM3168275
Metabolomic databases MetaboLights; MTBLS106
Other Wikidata; Q94094915
Entry history
Entry creation19-Dec-2019
Last entry update02-Jul-2020
Version number2