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Cellosaurus MCF-7 shWDR12-4 (CVCL_YJ25)

[Text version]

Cell line name MCF-7 shWDR12-4
Accession CVCL_YJ25
Resource Identification Initiative To cite this cell line use: MCF-7 shWDR12-4 (RRID:CVCL_YJ25)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Doubling time: 16-18 hours (CelloPub=CLPUB00550).
Knockout cell: Method=shRNA knockdown; HGNC; 14098; WDR12.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

CLPUB00550
Benhamron S.
Validating WDR12 as a potential drug target in triple negative breast cancer.
Thesis MSc (2019), University of Toronto, Canada

Cross-references
Other Wikidata; Q95986128
Entry history
Entry creation19-Dec-2019
Last entry update02-Jul-2020
Version number2