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Cellosaurus SK-BR-3 shWDR12-4 (CVCL_YJ28)

[Text version]

Cell line name SK-BR-3 shWDR12-4
Synonyms SKBR-3 shWDR12-4
Accession CVCL_YJ28
Resource Identification Initiative To cite this cell line use: SK-BR-3 shWDR12-4 (RRID:CVCL_YJ28)
Comments Population: Caucasian.
Doubling time: 36-39 hours (CelloPub=CLPUB00550).
Knockout cell: Method=shRNA knockdown; HGNC; 14098; WDR12.
Sequence variations Gene deletion; HGNC; 1748; CDH1; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

CLPUB00550
Benhamron S.
Validating WDR12 as a potential drug target in triple negative breast cancer.
Thesis MSc (2019), University of Toronto, Canada

Cross-references
Other Wikidata; Q98132643
Entry history
Entry creation19-Dec-2019
Last entry update20-May-2021
Version number5