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Cellosaurus U2OS CHRM4 PKA-Nomad (CVCL_YK38)

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Cell line name U2OS CHRM4 PKA-Nomad
Synonyms PKA-Nomad-CHRM4; PKANomad-CHRM4; M4 Nomad; CHRM4 PKANomad
Accession CVCL_YK38
Resource Identification Initiative To cite this cell line use: U2OS CHRM4 PKA-Nomad (RRID:CVCL_YK38)
Comments Characteristics: Before PKA activation, the fluorescent biosensor is localized in the cellular membrane. After receptor activation, PKA is activated and this activated PKA leads to change in the structural folding of Nomad Biosensor that promotes its cellular relocation in the vesicular trafficking of the cells.
Transfected with: HGNC; 1953; CHRM4.
Transfected with: UniProtKB; Q6WV12; Pontellina plumata GFP2 (with p.Lys5Glu, p.Val117Met, p.Val149Asp, p.Val151Asp, p.Ala155Thr, p.Phe168Ser and p.Leu200Asp = TurboGFP).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac.
Derived from sampling site: Bone; tibia.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages http://www.innoprot.com/en_productos.asp?idsf=68&id=17&idp=492
Entry history
Entry creation19-Dec-2019
Last entry update12-Mar-2020
Version number2