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Cellosaurus U2OS CHRM5 DAG-Nomad (CVCL_YK40)

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Cell line name U2OS CHRM5 DAG-Nomad
Synonyms DAG-NOMAD Muscarinic 5; DAGNomad M5; DAGNOMAD M5
Accession CVCL_YK40
Resource Identification Initiative To cite this cell line use: U2OS CHRM5 DAG-Nomad (RRID:CVCL_YK40)
Comments Characteristics: In absence of DAG, the fluorescent biosensor is localized in the cellular membrane. An increase in this second messenger concentration leads to change in the structural folding of Nomad biosensor that promotes its cellular relocation in the vesicular trafficking of the cells.
Transfected with: HGNC; 1954; CHRM5.
Transfected with: UniProtKB; J9PBR7; Entacmaea quadricolor far-red fluorescent protein eqFP650.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac.
Derived from sampling site: Bone; tibia.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages http://www.innoprot.com/en_productos.asp?idsf=76&id=17&idp=482
Entry history
Entry creation19-Dec-2019
Last entry update12-Mar-2020
Version number2