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Cellosaurus VeroE6/TMPRSS2 (CVCL_YQ49)

[Text version]

Cell line name VeroE6/TMPRSS2
Accession CVCL_YQ49
Resource Identification Initiative To cite this cell line use: VeroE6/TMPRSS2 (RRID:CVCL_YQ49)
Comments Group: Non-human primate cell line.
Group: SARS-CoV2 research cell line.
Characteristics: Highly susceptible to Middle East respiratory syndrome coronavirus (MERS-CoV), SARS coronavirus (SARS-CoV) and SARS coronavirus 2 (SARS-CoV-2) infection (PubMed=32165541).
Transfected with: HGNC; 11876; TMPRSS2.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from sampling site: Kidney; epithelium.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0574 (Vero C1008)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=31013314; DOI=10.1371/journal.pone.0215822
Nao N., Sato K., Yamagishi J., Tahara M., Nakatsu Y., Seki F., Katoh H., Ohnuma A., Shirogane Y., Hayashi M., Suzuki T., Kikuta H., Nishimura H., Takeda M.
Consensus and variations in cell line specificity among human metapneumovirus strains.
PLoS ONE 14:E0215822-E0215822(2019)

PubMed=32165541; DOI=10.1073/pnas.2002589117
Matsuyama S., Nao N., Shirato K., Kawase M., Saito S., Takayama I., Nagata N., Sekizuka T., Katoh H., Kato F., Sakata M., Tahara M., Kutsuna S., Ohmagari N., Kuroda M., Suzuki T., Kageyama T., Takeda M.
Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.
Proc. Natl. Acad. Sci. U.S.A. 117:7001-7003(2020)

Cell line collections JCRB; JCRB1819
Other Wikidata; Q91354600
Entry history
Entry creation12-Mar-2020
Last entry update20-May-2021
Version number3