ID   VeroE6/TMPRSS2
AC   CVCL_YQ49
DR   JCRB; JCRB1819
DR   Wikidata; Q91354600
RX   PubMed=31013314;
RX   PubMed=32165541;
CC   Group: Non-human primate cell line.
CC   Group: SARS-CoV-2 research cell line.
CC   Characteristics: Highly susceptible to Middle East respiratory syndrome coronavirus (MERS-CoV), SARS coronavirus (SARS-CoV) and SARS coronavirus 2 (SARS-CoV-2) infection (PubMed=32165541).
CC   Transfected with: HGNC; 11876; TMPRSS2.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from sampling site: Kidney; epithelium.
OX   NCBI_TaxID=60711; ! Chlorocebus sabaeus
HI   CVCL_0574 ! Vero C1008
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 12-03-20; Last updated: 23-09-21; Version: 4
//
RX   PubMed=31013314; DOI=10.1371/journal.pone.0215822;
RA   Nao N., Sato K., Yamagishi J., Tahara M., Nakatsu Y., Seki F.,
RA   Katoh H., Ohnuma A., Shirogane Y., Hayashi M., Suzuki T., Kikuta H.,
RA   Nishimura H., Takeda M.;
RT   "Consensus and variations in cell line specificity among human
RT   metapneumovirus strains.";
RL   PLoS ONE 14:E0215822-E0215822(2019).
//
RX   PubMed=32165541; DOI=10.1073/pnas.2002589117;
RA   Matsuyama S., Nao N., Shirato K., Kawase M., Saito S., Takayama I.,
RA   Nagata N., Sekizuka T., Katoh H., Kato F., Sakata M., Tahara M.,
RA   Kutsuna S., Ohmagari N., Kuroda M., Suzuki T., Kageyama T.,
RA   Takeda M.;
RT   "Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 117:7001-7003(2020).
//