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Cellosaurus BT474 A3 (CVCL_YX79)

[Text version]

Cell line name BT474 A3
Synonyms BT474-A3
Accession CVCL_YX79
Resource Identification Initiative To cite this cell line use: BT474 A3 (RRID:CVCL_YX79)
Comments Transfected with: HGNC; 2594; CYP19A1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Sequence variations Heterozygous for MAPK1 p.His61Gln (c.183C>G) (from parent cell line).
Heterozygous for PIK3CA p.Lys111Asn (c.333G>C) (ClinVar=VCV000376483) (from parent cell line).
Homozygous for TP53 p.Glu285Lys (c.853G>A) (ClinVar=VCV000420133) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0179 (BT-474)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=20386540; DOI=10.1038/sj.bjc.6605641
Evans A.H., Pancholi S., Farmer I., Thornhill A., Evans D.B., Johnston S.R.D., Dowsett M., Martin L.-A.
EGFR/HER2 inhibitor AEE788 increases ER-mediated transcription in HER2/ER-positive breast cancer cells but functions synergistically with endocrine therapy.
Br. J. Cancer 102:1235-1243(2010)

Cross-references
Other Wikidata; Q93432844
Entry history
Entry creation12-Mar-2020
Last entry update02-Jul-2020
Version number2