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Cellosaurus SKBR3 A3 (CVCL_YX81)

[Text version]

Cell line name SKBR3 A3
Accession CVCL_YX81
Resource Identification Initiative To cite this cell line use: SKBR3 A3 (RRID:CVCL_YX81)
Comments Transfected with: HGNC; 2594; CYP19A1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Sequence variations Homozygous for CDH1 deletion (from parent cell line).
Homozygous for TP53 p.Arg175His (c.524G>A) (ClinVar=VCV000012374) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=20386540; DOI=10.1038/sj.bjc.6605641
Evans A.H., Pancholi S., Farmer I., Thornhill A., Evans D.B., Johnston S.R.D., Dowsett M., Martin L.-A.
EGFR/HER2 inhibitor AEE788 increases ER-mediated transcription in HER2/ER-positive breast cancer cells but functions synergistically with endocrine therapy.
Br. J. Cancer 102:1235-1243(2010)

Entry history
Entry creation12-Mar-2020
Last entry update02-Jul-2020
Version number2