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Cellosaurus MKN45/CDDP/R1 (CVCL_YX96)

[Text version]
Cell line name MKN45/CDDP/R1
Accession CVCL_YX96
Resource Identification Initiative To cite this cell line use: MKN45/CDDP/R1 (RRID:CVCL_YX96)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=18751380
Tozawa K., Oshima T., Kobayashi T., Yamamoto N., Hayashi C., Matsumoto T., Miwa H.
Oxaliplatin in treatment of the cisplatin-resistant MKN45 cell line of gastric cancer.
Anticancer Res. 28:2087-2092(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_YX96
Encyclopedic resources Wikidata; Q95989944
Entry history
Entry creation12-Mar-2020
Last entry update05-Oct-2023
Version number7