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Cellosaurus 3T3 rho-0#8 (CVCL_YY06)

Cell line name 3T3 rho-0#8
Accession CVCL_YY06
Resource Identification Initiative To cite this cell line use: 3T3 rho-0#8 (RRID:CVCL_YY06)
Comments Characteristics: Cell line devoid of mitochondrial DNA (rho0). Produced by transient transfection with plasmid pMA4008 encoding HSV-1 UL12.5M185 protein, which damages mtDNA by an unknown mechanism.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=27136098; DOI=10.1371/journal.pone.0154684
Spadafora D., Kozhukhar N., Chouljenko V.N., Kousoulas K.G., Alexeyev M.F.
Methods for efficient elimination of mitochondrial DNA from cultured cells.
PLoS ONE 11:E0154684-E0154684(2016)

Cross-references
Cell line collections (Providers) Kerafast; ESA101
Encyclopedic resources Wikidata; Q98125394
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number5