ID   MDCK.STAT1 KO
AC   CVCL_YZ44
SY   MDCK.STAT1-KO; MDCK.STAT1KO
DR   ATCC; CCL-34-VHG
DR   Wikidata; Q98127201
RX   CelloPub=CLPUB00659;
CC   Group: Vaccine production cell line.
CC   Virology: Excellent cell model for virus propagation and viral vaccine production. It exhibits significant increased viral titer and enhanced virus production capability when compared to its parental cell line (ATCC=CCL-34-VHG).
CC   Doubling time: ~22 hours (ATCC=CCL-34-VHG).
CC   Knockout cell: Method=CRISPR/Cas9; VGNC; -; STAT1.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: Cocker Spaniel.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_0422 ! MDCK
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 02-07-20; Last updated: 05-10-23; Version: 8
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RX   CelloPub=CLPUB00659;
RA   Turner-Gillies E., Shapiro B.A., Tian F.;
RT   "Generation of cell lines capable of producing high-titer viral stocks
RT   for use in vaccine manufacture and gene therapy.";
RL   (In) ATCC application note AP-082021-v01; pp.1-8; ATCC; Manassas (2021).
//