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Cellosaurus Calu-3 2B4 (CVCL_YZ47)

[Text version]

Cell line name Calu-3 2B4
Synonyms 2B4
Accession CVCL_YZ47
Resource Identification Initiative To cite this cell line use: Calu-3 2B4 (RRID:CVCL_YZ47)
Comments Characteristics: Clone of Calu-3 with increased expression of ACE2 and high susceptibility to SARS coronavirus (SARS-CoV) infection (PubMed=20090954).
Omics: Transcriptome analysis.
Sequence variations Homozygous for TP53 p.Met237Ile (c.711G>T) (ClinVar=VCV000634770) (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0609 (Calu-3)
Sex of cell Male
Age at sampling 25Y
Category Cancer cell line

PubMed=20090954; DOI=10.1371/journal.pone.0008729
Yoshikawa T., Hill T.E., Yoshikawa N., Popov V.L., Galindo C.L., Garner H.R., Peters C.J., Tseng C.-T.
Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection.
PLoS ONE 5:E8729-E8729(2010)

Gene expression databases GEO; GSE17400
Other Wikidata; Q98125608
Entry history
Entry creation02-Jul-2020
Last entry update29-Oct-2020
Version number2