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Cellosaurus IOSE19CMYC (CVCL_YZ55)

[Text version]
Cell line name IOSE19CMYC
Synonyms IOSE19+CMYC; IOE19CMYC
Accession CVCL_YZ55
Resource Identification Initiative To cite this cell line use: IOSE19CMYC (RRID:CVCL_YZ55)
Comments Transfected with: HGNC; 7553; MYC.
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transfected with: UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0T69 (IOSE19)
Children:
CVCL_YZ59 (IOSE19CMYC.BRAF)CVCL_YZ60 (IOSE19CMYC.KRAS)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=20360942; DOI=10.1593/neo.91948
Lawrenson K., Grun B., Benjamin E., Jacobs I.J., Dafou D., Gayther S.A.
Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer.
Neoplasia 12:317-325(2010)

PubMed=21859834; DOI=10.1093/carcin/bgr140
Lawrenson K., Sproul D., Grun B., Notaridou M., Benjamin E., Jacobs I.J., Dafou D., Sims A.H., Gayther S.A.
Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.
Carcinogenesis 32:1540-1549(2011)

PubMed=25204737; DOI=10.1002/ijc.29197
Lawrenson K., Mhawech-Fauceglia P., Worthington J., Spindler T.J., O'Brien D., Lee J.M., Spain G., Sharifian M., Wang G.-S., Darcy K.M., Pejovic T., Sowter H., Timms J.F., Gayther S.A.
Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the secretomes of three-dimensional genetic models of ovarian carcinogenesis.
Int. J. Cancer 137:1806-1817(2015)

Cross-references
Encyclopedic resources Wikidata; Q98126781
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number7