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Cellosaurus MDA-MB-231/Luciferase-2A-RFP (CVCL_YZ80)

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Cell line name MDA-MB-231/Luciferase-2A-RFP
Synonyms MDA-MB-231 / Luciferase-2A-RFP; MDA-MB-231 / Luc-RFP
Accession CVCL_YZ80
Resource Identification Initiative To cite this cell line use: MDA-MB-231/Luciferase-2A-RFP (RRID:CVCL_YZ80)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Characteristics: Transformed by lentivirus with a suCMV-Luc-2A-RFP-RSV-Bsr construct.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; Q9U6Y8; RFP.
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Web pages https://www.gentarget.com/product/mda-mb-231-luc-rfp-stable-cell-line/
Entry history
Entry creation02-Jul-2020
Last entry update02-Jul-2020
Version number1