ID   IDE8
AC   CVCL_Z167
DR   ATCC; CRL-11973
DR   Wikidata; Q54897298
RX   Patent=US5869335;
RX   PubMed=8057317;
RX   PubMed=8064520;
RX   PubMed=8812616;
RX   PubMed=15053931;
RX   PubMed=17662657;
RX   PubMed=20388200;
RX   PubMed=22743047;
RX   PubMed=29017825;
RX   PubMed=29886187;
RX   PubMed=32158404;
WW   https://www.liverpool.ac.uk/health-and-life-sciences/research/liverpool-shared-research-facilities/bio-resources/tick-cell-biobank/tick-cell-lines/
WW   https://www.dsmz.de/fileadmin/Bereiche/Microbiology/Dateien/Kultivierungshinweise/TickCellCultureMethods-4.pdf
WW   https://www.vectorbase.org/vbsearch/details/VBRNAseq_group_1255
CC   Group: Patented cell line.
CC   Group: Tick cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11973.
CC   Omics: Transcriptome analysis by RNAseq.
OX   NCBI_TaxID=6945; ! Ixodes scapularis (Black-legged tick)
SX   Mixed sex
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 10-04-15; Last updated: 21-03-23; Version: 12
//
RX   Patent=US5869335;
RA   Munderloh U.G., Kurtti T.J., Kocan K.M., Blouin E.F., Ewing S.A.;
RT   "Propagating bovine parasite by incubation of undifferentiated cells
RT   under low oxygen increased carbon dioxide, with organic buffers;
RT   efficient, large scale production; diagnosis/vaccine for rocky
RT   mountains spotted fever.";
RL   Patent number US5869335, 09-Feb-1999.
//
RX   PubMed=8057317; DOI=10.1093/jmedent/31.3.425;
RA   Chen C.-S., Munderloh U.G., Kurtti T.J.;
RT   "Cytogenetic characteristics of cell lines from Ixodes scapularis
RT   (Acari: Ixodidae).";
RL   J. Med. Entomol. 31:425-434(1994).
//
RX   PubMed=8064520; DOI=10.2307/3283188;
RA   Munderloh U.G., Liu Y., Wang M.-M., Chen C.-S., Kurtti T.J.;
RT   "Establishment, maintenance and description of cell lines from the
RT   tick Ixodes scapularis.";
RL   J. Parasitol. 80:533-543(1994).
//
RX   PubMed=8812616; DOI=10.1006/jipa.1996.0050;
RA   Kurtti T.J., Munderloh U.G., Andreadis T.G., Magnarelli L.A.,
RA   Mather T.N.;
RT   "Tick cell culture isolation of an intracellular prokaryote from the
RT   tick Ixodes scapularis.";
RL   J. Invertebr. Pathol. 67:318-321(1996).
//
RX   PubMed=15053931; DOI=10.1016/j.jcpa.2003.12.002;
RA   Bell-Sakyi L.;
RT   "Ehrlichia ruminantium grows in cell lines from four ixodid tick
RT   genera.";
RL   J. Comp. Pathol. 130:285-293(2004).
//
RX   PubMed=17662657; DOI=10.1016/j.pt.2007.07.009;
RA   Bell-Sakyi L., Zweygarth E., Blouin E.F., Gould E.A., Jongejan F.;
RT   "Tick cell lines: tools for tick and tick-borne disease research.";
RL   Trends Parasitol. 23:450-457(2007).
//
RX   PubMed=20388200; DOI=10.1186/1756-3305-3-37;
RA   Lallinger G., Zweygarth E., Bell-Sakyi L., Passos L.M.F.;
RT   "Cold storage and cryopreservation of tick cell lines.";
RL   Parasit. Vectors 3:37.1-37.6(2010).
//
RX   PubMed=22743047; DOI=10.1016/j.ttbdis.2012.05.002;
RA   Alberdi M.P., Dalby M.J., Rodriguez-Andres J., Fazakerley J.K.,
RA   Kohl A., Bell-Sakyi L.;
RT   "Detection and identification of putative bacterial endosymbionts and
RT   endogenous viruses in tick cell lines.";
RL   Ticks Tick Borne Dis. 3:137-146(2012).
//
RX   PubMed=29017825; DOI=10.1016/j.ttbdis.2017.09.014;
RA   Tjale M.A., Pretorius A., Josemans A.I., Van Kleef M., Liebenberg J.;
RT   "Transcriptomic analysis of Ehrlichia ruminantium during the
RT   developmental stages in bovine and tick cell culture.";
RL   Ticks Tick Borne Dis. 9:126-134(2018).
//
RX   PubMed=29886187; DOI=10.1016/j.ttbdis.2018.05.015;
RA   Bell-Sakyi L., Darby A.C., Baylis M., Makepeace B.L.;
RT   "The Tick Cell Biobank: a global resource for in vitro research on
RT   ticks, other arthropods and the pathogens they transmit.";
RL   Ticks Tick Borne Dis. 9:1364-1371(2018).
//
RX   PubMed=32158404; DOI=10.3389/fphys.2020.00152;
RA   Al-Rofaai A., Bell-Sakyi L.;
RT   "Tick cell lines in research on tick control.";
RL   Front. Physiol. 11:152.1-152.7(2020).
//