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Cellosaurus Tn-4h (CVCL_Z431)

[Text version]
Cell line name Tn-4h
Synonyms BTI-Tn-5B1-4h; Tn4h; 4h
Accession CVCL_Z431
Resource Identification Initiative To cite this cell line use: Tn-4h (RRID:CVCL_Z431)
Comments Group: Insect cell line.
Group: Patented cell line.
Group: Recombinant protein production insect cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-2355.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Trichoplusia ni (Cabbage looper) (NCBI Taxonomy: 7111)
Hierarchy Parent: CVCL_C190 (BTI-Tn-5B1-4)
Children:
CVCL_Z432 (Tn-4s)
Sex of cell Sex unspecified
Age at sampling Embryonic stage
Category Spontaneously immortalized cell line
Publications

PubMed=10933841; DOI=10.1021/bp000057p
Joshi L., Davis T.R., Mattu T.S., Rudd P.M., Dwek R.A., Shuler M.L., Wood H.A.
Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein.
Biotechnol. Prog. 16:650-656(2000)

PubMed=11587569; DOI=10.1021/bp010071h
Joshi L., Shuler M.L., Wood H.A.
Production of a sialylated N-linked glycoprotein in insect cells.
Biotechnol. Prog. 17:822-827(2001)

Patent=US6472175
Wood H.A.
Sialylation of N-linked glycoproteins in the baculovirus expression vector system.
Patent number US6472175, 29-Oct-2002

PubMed=20574041; DOI=10.1093/glycob/cwq099
Hillar A., Jarvis D.L.
Re-visiting the endogenous capacity for recombinant glycoprotein sialylation by baculovirus-infected Tn-4h and DpN1 cells.
Glycobiology 20:1323-1330(2010)

Cross-references
Cell line databases/resources ICLDB; tn-4h
Encyclopedic resources Wikidata; Q54972716
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number8