Home  |  Contact

Cellosaurus SK-astrocyte-IDH1-R132H (CVCL_Z596)

[Text version]
Cell line name SK-astrocyte-IDH1-R132H
Accession CVCL_Z596
Resource Identification Initiative To cite this cell line use: SK-astrocyte-IDH1-R132H (RRID:CVCL_Z596)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2012-113.
Transfected with: HGNC; 5382; IDH1 (with p.Arg132His).
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Telomerase immortalized cell line
Publications

PubMed=22343889; DOI=10.1038/nature10866
Turcan S., Rohle D., Goenka A., Walsh L.A., Fang F., Yilmaz E., Campos C., Fabius A.W.M., Lu C., Ward P.S., Thompson C.B., Kaufman A., Guryanova O., Levine R., Heguy A., Viale A.J., Morris L.G.T., Huse J.T., Mellinghoff I.K., Chan T.A.
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
Nature 483:479-483(2012)

Cross-references
Encyclopedic resources Wikidata; Q54953610
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number10