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Cellosaurus RKO SIRT1 KO (CVCL_ZC46)

[Text version]

Cell line name RKO SIRT1 KO
Accession CVCL_ZC46
Resource Identification Initiative To cite this cell line use: RKO SIRT1 KO (RRID:CVCL_ZC46)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; 14929; SIRT1.
Sequence variations Heterozygous for ACVR2A p.Lys437fs*19 (c.1309_1310delAA) and p.Lys437fs*5 (c.1310delA) (from parent cell line).
Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (from parent cell line).
PIK3CA p.His1047Arg (c.3140A>G) (ClinVar=VCV000013652) (from parent cell line).
Heterozygous for TGFBR2 p.Lys128Serfs*35 (c.383delA) and p.Leu452Pro (c.1355T>C) (from parent cell line).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0504 (RKO)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Cell line collections Kerafast; ENH132-FP
Entry history
Entry creation02-Jul-2020
Last entry update02-Jul-2020
Version number1