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Cellosaurus 293T PCC/ERR reporter (CVCL_ZD88)

[Text version]
Cell line name 293T PCC/ERR reporter
Synonyms ERRalpha/PGC-1alpha Expressing HEK-293T/17 Cell Line; PGC/ERR reporter
Accession CVCL_ZD88
Resource Identification Initiative To cite this cell line use: 293T PCC/ERR reporter (RRID:CVCL_ZD88)
Comments Characteristics: Expresses a construct with a pleiotropic nuclear receptor enhancer MHRE that controls the expression of GFP and luciferase (AAB-GFP-Luc).
Transfected with: HGNC; 3471; ESRRA.
Transfected with: HGNC; 9237; PPARGC1A.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1926 (HEK293T/17)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=28346099; DOI=10.1177/2472555216689772
Teng C.T., Hsieh J.-H., Zhao J.-H., Huang R.-L., Xia M.-H., Martin N., Gao X.-H., Dixon D., Auerbach S.S., Witt K.L., Merrick B.A.
Development of novel cell lines for high-throughput screening to detect estrogen-related receptor alpha modulators.
SLAS Discov. 22:720-731(2017)

Cross-references
Cell line collections (Providers) Kerafast; ENH071-FP
Encyclopedic resources Wikidata; Q98125375
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number6