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Cellosaurus T-47D HA-PEROXO (CVCL_ZM09)

[Text version]

Cell line name T-47D HA-PEROXO
Synonyms T47D HA-PEROXO
Accession CVCL_ZM09
Resource Identification Initiative To cite this cell line use: T-47D HA-PEROXO (RRID:CVCL_ZM09)
Comments Characteristics: Expresses PEROXO-Tag, a chimeric protein consisting of three HA epitopes attached to the N-terminus of mEGFP and a segment of PEX26 fused to the EGFP C-terminus. This tag allows for localization to and insertion into the peroxisomal membrane.
Transfected with: HGNC; 22965; PEX26 (with Met1_Val236del).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line

PubMed=32417403; DOI=10.1016/j.isci.2020.101109
Ray G.J., Boydston E.A., Shortt E., Wyant G.A., Lourido S., Chen W.W., Sabatini D.M.
A PEROXO-Tag enables rapid isolation of peroxisomes from human cells.
IScience 23:101109-101109(2020)

Other Wikidata; Q98133057
Entry history
Entry creation02-Jul-2020
Last entry update20-May-2021
Version number3