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Cellosaurus ATL2ABR (CVCL_ZT68)

[Text version]
Cell line name ATL2ABR
Synonyms Ataxia Telangiectasia-Like 2 Australia BRisbane
Accession CVCL_ZT68
Resource Identification Initiative To cite this cell line use: ATL2ABR (RRID:CVCL_ZT68)
Comments Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Ataxia-oculomotor apraxia type 3 (NCIt: C173403)
Spinocerebellar ataxia with axonal neuropathy type 2 (ORDO: Orphanet_64753)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZW04 ! PSF [Human AOA3 fibroblast]
Category Transformed cell line
Publications

PubMed=16540636; DOI=10.1158/0008-5472.CAN-05-3428
Gueven N., Becherel O.J., Birrell G., Chen P., DelSal G., Carney J.P., Grattan-Smith P., Lavin M.F.
Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype.
Cancer Res. 66:2907-2912(2006)

PubMed=17347666; DOI=10.1038/sj.cdd.4402116
Gueven N., Becherel O.J., Howe O., Chen P., Haince J.-F., Ouellet M.-E., Poirier G.G., Waterhouse N., Fusser M., Epe B., de Murcia J.M., de Murcia G., McGowan C.H., Parton R., Mothersill C., Grattan-Smith P., Lavin M.F.
A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance.
Cell Death Differ. 14:1149-1161(2007)

PubMed=25868131; DOI=10.1016/j.mrgentox.2015.03.012
Kobayashi J., Saito Y., Okui M., Miwa N., Komatsu K.
Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses.
Mutat. Res. 782:42-50(2015)

Cross-references
Encyclopedic resources Wikidata; Q98125520
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number4