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Cellosaurus HaCaT-shNrf2#2 (CVCL_ZW71)

[Text version]

Cell line name HaCaT-shNrf2#2
Accession CVCL_ZW71
Resource Identification Initiative To cite this cell line use: HaCaT-shNrf2#2 (RRID:CVCL_ZW71)
Comments Knockout cell: Method=shRNA knockdown; HGNC; 7782; NFE2L2.
Transfected with: UniProtKB; P13249; S.alboniger pac.
Derived from sampling site: Back; skin; epidermis; keratinocyte.
Sequence variations Heterozygous for TP53 p.His179Tyr (c.535C>T) (ClinVar=VCV000127815) (from parent cell line).
Heterozygous for TP53 p.Arg282Trp (c.843_844CC>TT) (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line

PubMed=31319135; DOI=10.1016/j.tiv.2019.104602
Choi M., Park M., Lee S., Lee J.W., Choi W.J., Lee C.
Establishment of Nrf2-deficient HaCaT and immortalized primary human foreskin keratinocytes and characterization of their responses to ROS-induced cytotoxicity.
Toxicol. In Vitro 61:104602-104602(2019)

Other Wikidata; Q102114091
Entry history
Entry creation29-Oct-2020
Last entry update12-Jan-2021
Version number2