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Cellosaurus SW620/AD300 (CVCL_ZZ39)

[Text version]

Cell line name SW620/AD300
Synonyms SW620/AD-300; SW620/Ad300; SW620 Ad300; Ad300
Accession CVCL_ZZ39
Resource Identification Initiative To cite this cell line use: SW620/AD300 (RRID:CVCL_ZZ39)
Comments Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Sequence variations Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line

PubMed=14871996; DOI=10.1158/1078-0432.ccr-1044-3
Hu Y.-P., Krishan A., Nie W.-J., Sridhar K.S., Mayer L.D., Bally M.
Synergistic cytotoxicity of pyrazoloacridine with doxorubicin, etoposide, and topotecan in drug-resistant tumor cells.
Clin. Cancer Res. 10:1160-1169(2004)

Other Wikidata; Q102114957
Entry history
Entry creation29-Oct-2020
Last entry update20-May-2021
Version number3