Home  |  Contact

Cellosaurus publication CLPUB00328

Publication number CLPUB00328
Authors Earley E., Johnson K.
Title The lineage of Vero, Vero 76 and its clone C1008 in the United States.
Citation (In) Vero cells: origin, properties and biomedical applications; Simizu B., Terasima T. (eds.); pp.26-29; Department of Microbiology School of Medicine Chiba University; Chiba (1988)
Abstract On June 15, 1964, Dr. Bunsiti Simizu from the Department of Microbiology of the Chiba University School of Medicine in Chiba, Japan arrived as a visiting fellow to work with Dr. Ned Wiebenga in the Laboratory of Tropical Virology (LTV), at the National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland. Dr. Simizu brought with him several seed cultures of passage (P) 93 of the continuous cell line designated Vero. Vero was initiated and developed from kidney tissue of a normal African green monkey, Cercopithecus aethiops, by Drs. Y. Yasumura and Y. Kawakita at Chiba University. At that time, we were working at LTV and were stationed at Middle America Research Unit (MARU) Balboa, Panama Canal Zone. Much of the emphasis of our work was on arboviruses and other related tropical zoonotic viruses. Of primary interest was Machupo virus, the causative agent of Bolivian hemorrhagic fever. This virus had been isolated at MARU a year earlier and we sought a cell line suitable for quantitive viral assays and neutralization tests. Drs. Wiebenga and Simizu reported successful production of virus plaques with Machupo and several other zoonotic viruses in Vero.
Cell lines CVCL_0059; Vero
CVCL_0603; Vero 76
CVCL_0574; Vero C1008