||Gastric cancer is not only the most frequently seen cancer in Japan, but
also has a variety of histological features among cancers, so it is of
great pathological interest in terms of its origin or cell differentiation.
It is a tumor that is leaning against. On the other hand, in recent years,
culturing of human cancer cells has been enthusiastically attempted due to
various demands, and cultured cell lines are being established for various
types of human cancers. 1. However, the number of gastric cancer cell
cultures established is extremely small. I tried culturing gastric cancer
cells and was able to establish four new subculture strains with different
origin histological types. In addition to these, one strain was
distributed, and morphological search by light and electron microscopy,
xenotransplantation, and induction of cell differentiation by cAMP were
performed on each of the five cell lines. In the wood paper, we report
mainly on the origin and differentiation of gastric cancer cells, and the
relationship between in vitro growth morphology and in vivo histology.