_____ _ _ / ____| | | | | | ___| | | ___ ___ __ _ _ _ _ __ _ _ ___ | | / _ \ | |/ _ \/ __|/ _` | | | | '__| | | / __| | |___| __/ | | (_) \__ \ (_| | |_| | | | |_| \__ \ \_____\___|_|_|\___/|___/\__,_|\__,_|_| \__,_|___/ This is the release notes for Cellosaurus version 28 of November 2018. 1) Statistics 109135 cell lines (81617 human, 19451 mouse, 1952 rat) 603 species represented 70021 synonyms 324705 cross-references to 80 ontologies, databases, catalogs, etc. 89915 references to 16131 distinct publications (papers, patents, theses, etc.) 16922 web links 5916 human and dog cell lines with STR profiles (from 373 distinct sources) 2) Changes in the CC lines 2a) New "HLA typing" CC line topic. We are now capturing information on the HLA alleles that are present in human cell lines. This data is stored in a new CC line type: 'HLA typing". Examples: CC HLA typing: A*03,25; B*37:01:01:01,47:01:01:03; C*06; DPA1*01; DPB1*04:01:01; DQA1*01:01:01:01,01:03:01; DQB1*05:01:01;06:03:01:02; DRB1*01:01:01,14:17 (IMGT/HLA; 10074). CC HLA typing: A*23:01,24:02:01; B*35:02,44:03:01; C*04:01:01:01; DPB1*02:01:02,10:01; DQB1*02:02,03; DRB1*07:01,11:04:01 (PubMed=15748285). 3) Changes in the DR lines 3a) Cross-references were added to the FujiFilm Cellular Dynamics (FCDI) cell lines. Corresponding entry in the file cellosaurus_xrefs.txt: Abbrev: FCDI Name : FujiFilm Cellular Dynamics, Inc Server: https://fujifilmcdi.com/the-cirm-ipsc-bank Db_URL: None Cat : Cell line databases/resources // Example: DR FCDI; CW10001 3b) Cross-references were added to KYinno cell lines. Corresponding entry in the file cellosaurus_xrefs.txt: Abbrev: KYinno Name : KYinno cell lines Server: http://www.kyinno.com/ Db_URL: https://innopedia.kyinno.com/DataBase/CellLine.aspx?file=%s.pdf Cat : Cell line collections // Example: DR KYinno; KC-0127 ---------------------------------------- Amos Bairoch CALIPHO group; neXtProt project SIB - Swiss Institute of Bioinformatics Geneva; Switzerland ----------------------------------------