Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > PMC42
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Breast Carcinoma Cell Line |
Description | A highly rearranged, near tetraploid cell line derived by Whitehead R et al., 1983 and obtained from Dr Mike O'Hare. |
Notable Features | Translocations involve 2, 3, 7, 8, 9, 10, 11, 14, 15, 16, 17, 18, 19 and X. Deletions were detected on chromosomes 1, 2, 3, 8 and 11. |
Representative SKY Karyotype | |
57(52-67).1x2, del(1)(q?), 2x1, del(2)(p?), 3x1, del(3)(p?), der(3)t(3;11), 4x2, 5x4, 6x2, 7x3, der(7)t(7;10), 8x2, del(8)(q?), 9x2, 10x2, 11x1, del(11)(p?), der(11)t(9;11)x2, 12x3, 13x2, 14x2, der(14)t(10;14), 15x3, 16x2, der(16)t(16;17), 17x2, 18x2, der(?)t(8;18), 19x1, der(19)t(2;19)x2, der(19)t(15;19), 20x4, 21x2, 22x2, Xx1, der(X)t(X;2) cp[10] | |
CGH results | |
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