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ProtParam [Documentation / Reference] is a tool which allows the computation of various physical and chemical parameters for a given protein stored in UniProtKB or for a user entered protein sequence. The computed parameters include the molecular weight, theoretical pI, amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, aliphatic index and grand average of hydropathicity (GRAVY) (Disclaimer).

Enter a protein sequence

Please enter one UniProtKB AC/ID (e.g. P05130 or KPC1_DROME).
Alternatively, enter one protein sequence in single letter code (e.g. ABCDEFGHIKLMNOPQRSTUVWXY).