Variant position: 1151 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 2137 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human QTDPEYLLLGQRLEGLDTGW NALGRMWESRSHTLAQCLGFQ
Mouse QTDPDYQLLGQRLEGLDTDW DALRRMWESRGNTLTQCLGFQ
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Full-length sequence of the cDNA for human erythroid beta-spectrin.
Winkelmann J.C.; Chang J.G.; Tse W.T.; Scarpa A.L.; Marchesi V.T.; Forget B.G.;
J. Biol. Chem. 265:11827-11832(1990)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3); VARIANTS ASN-439 AND ASP-1151;
Beta spectrin in human skeletal muscle. Tissue-specific differential processing of 3' beta spectrin pre-mRNA generates a beta spectrin isoform with a unique carboxyl terminus.
Winkelmann J.C.; Costa F.F.; Linzie B.L.; Forget B.G.;
J. Biol. Chem. 265:20449-20454(1990)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1055-2137 (ISOFORM 2); VARIANT ASP-1151;
Identification of an unusual deletion within homologous repeats of human reticulocyte beta-spectrin and probable peptide polymorphism.
Yoon S.H.; Kentros C.G.; Prchal J.T.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 928-1756 (ISOFORMS 1/2/3); VARIANT ASP-1151;
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