Variant position: 91 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 142 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VAHVDDMPNALSALSDLHAH KLRVDPVNFKLLSHCLLVTLA
Gorilla VAHVDDMPNALSALSDLHAH KLRVDPVNFKLLSHCLLVTLA
Rhesus macaque VGHVDDMPNALSALSDLHAH KLRVDPVNFKLLSHCLLVTLA
Chimpanzee VAHVDDMPNALSALSDLHAH KLRVDPVNFKLLSHCLLVTLA
Mouse AGHLDDLPGALSALSDLHAH KLRVDPVNFKLLSHCLLVTLA
Rat ADHVEDLPGALSTLSDLHAH KLRVDPVNFKFLSHCLLVTLA
Pig VGHLDDLPGALSALSDLHAH KLRVDPVNFKLLSHCLLVTLA
Bovine VEHLDDLPGALSELSDLHAH KLRVDPVNFKLLSHSLLVTLA
Rabbit VGHLDDLPGALSTLSDLHAH KLRVDPVNFKLLSHCLLVTLA
Sheep VGHLDDLPGTLSDLSDLHAH KLRVDPVNFKLLSHSLLVTLA
Cat VAHMDDLPTAMSALSDLHAY KLRVDPVNFKFLSHCLLVTLA
Horse VGHLDDLPGALSNLSDLHAH KLRVDPVNFKLLSHCLLSTLA
Chicken ANHIDDIAGTLSKLSDLHAH KLRVDPVNFKLLGQCFLVVVA
Xenopus tropicalis CNHLDNIAGCLSKLSDLHAY DLRVDPGNFPLLAHQILVVVA
Zebrafish ISKIDDLVGGLAALSELHAF KLRVDPANFKILSHNVIVVIA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
HB Handa [alpha 90 (FG 2) Lys replaced by Met]: structure and biosynthesis of a new slightly higher oxygen affinity variant.
Harano T.; Harano K.; Shibata S.; Ueda S.; Imai K.; Seki M.;
Cited for: VARIANT HANDA MET-91;
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