Variant position: 100 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 142 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ALSALSDLHAHKLRVDPVNF KLLSHCLLVTLAAHLPAEFTP
Gorilla ALSALSDLHAHKLRVDPVNF KLLSHCLLVTLAAHLPAEFTP
Rhesus macaque ALSALSDLHAHKLRVDPVNF KLLSHCLLVTLAAHLPAEFTP
Chimpanzee ALSALSDLHAHKLRVDPVNF KLLSHCLLVTLAAHLPAEFTP
Mouse ALSALSDLHAHKLRVDPVNF KLLSHCLLVTLASHHPADFTP
Rat ALSTLSDLHAHKLRVDPVNF KFLSHCLLVTLACHHPGDFTP
Pig ALSALSDLHAHKLRVDPVNF KLLSHCLLVTLAAHHPDDFNP
Bovine ALSELSDLHAHKLRVDPVNF KLLSHSLLVTLASHLPSDFTP
Rabbit ALSTLSDLHAHKLRVDPVNF KLLSHCLLVTLANHHPSEFTP
Sheep TLSDLSDLHAHKLRVDPVNF KLLSHSLLVTLACHLPNDFTP
Cat AMSALSDLHAYKLRVDPVNF KFLSHCLLVTLACHHPAEFTP
Horse ALSNLSDLHAHKLRVDPVNF KLLSHCLLSTLAVHLPNDFTP
Chicken TLSKLSDLHAHKLRVDPVNF KLLGQCFLVVVAIHHPAALTP
Xenopus tropicalis CLSKLSDLHAYDLRVDPGNF PLLAHQILVVVAIHFPKQFDP
Zebrafish GLAALSELHAFKLRVDPANF KILSHNVIVVIAMLFPADFTP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
A new alpha chain variant, Hb Turriff [alpha 99(G6)Lys-->Glu]: the interference of abnormal hemoglobins in Hb A1c determination.
Langdown J.V.; Davidson R.J.; Williamson D.;
Cited for: VARIANT TURRIFF GLU-100;
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