Variant position: 103 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 142 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ALSDLHAHKLRVDPVNFKLL SHCLLVTLAAHLPAEFTPAVH
Gorilla ALSDLHAHKLRVDPVNFKLL SHCLLVTLAAHLPAEFTPAVH
Rhesus macaque ALSDLHAHKLRVDPVNFKLL SHCLLVTLAAHLPAEFTPAVH
Chimpanzee ALSDLHAHKLRVDPVNFKLL SHCLLVTLAAHLPAEFTPAVH
Mouse ALSDLHAHKLRVDPVNFKLL SHCLLVTLASHHPADFTPAVH
Rat TLSDLHAHKLRVDPVNFKFL SHCLLVTLACHHPGDFTPAMH
Pig ALSDLHAHKLRVDPVNFKLL SHCLLVTLAAHHPDDFNPSVH
Bovine ELSDLHAHKLRVDPVNFKLL SHSLLVTLASHLPSDFTPAVH
Rabbit TLSDLHAHKLRVDPVNFKLL SHCLLVTLANHHPSEFTPAVH
Sheep DLSDLHAHKLRVDPVNFKLL SHSLLVTLACHLPNDFTPAVH
Cat ALSDLHAYKLRVDPVNFKFL SHCLLVTLACHHPAEFTPAVH
Horse NLSDLHAHKLRVDPVNFKLL SHCLLSTLAVHLPNDFTPAVH
Chicken KLSDLHAHKLRVDPVNFKLL GQCFLVVVAIHHPAALTPEVH
Xenopus tropicalis KLSDLHAYDLRVDPGNFPLL AHQILVVVAIHFPKQFDPATH
Zebrafish ALSELHAFKLRVDPANFKIL SHNVIVVIAMLFPADFTPEVH
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
The characterization of hemoglobin Manitoba or alpha (2)102(G9)Ser----Arg beta 2 and hemoglobin Contaldo or alpha (2)103(G10)His----Arg beta 2 by high performance liquid chromatography.
Sciarratta G.V.; Ivaldi G.; Molaro G.L.; Sansone G.; Salkie M.L.; Wilson J.B.; Reese A.L.; Huisman T.H.;
Cited for: VARIANT MANITOBA ARG-103; VARIANT CONTALDO ARG-104;
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