Variant position: 127 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 142 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human LVTLAAHLPAEFTPAVHASL DKFLASVSTVLTSKYR
Gorilla LVTLAAHLPAEFTPAVHASL DKFLASVSTVLTSKYR
Rhesus macaque LVTLAAHLPAEFTPAVHASL DKFLASVSTVLTSKYR
Chimpanzee LVTLAAHLPAEFTPAVHASL DKFLASVSTVLTSKYR
Mouse LVTLASHHPADFTPAVHASL DKFLASVSTVLTSKYR
Rat LVTLACHHPGDFTPAMHASL DKFLASVSTVLTSKYR
Pig LVTLAAHHPDDFNPSVHASL DKFLANVSTVLTSKYR
Bovine LVTLASHLPSDFTPAVHASL DKFLANVSTVLTSKYR
Rabbit LVTLANHHPSEFTPAVHASL DKFLANVSTVLTSKYR
Sheep LVTLACHLPNDFTPAVHASL DKFLANVSTVLTSKYR
Cat LVTLACHHPAEFTPAVHASL DKFFSAVSTVLTSKYR
Horse LSTLAVHLPNDFTPAVHASL DKFLSSVSTVLTSKYR
Chicken LVVVAIHHPAALTPEVHASL DKFLCAVGTVLTAKYR
Xenopus tropicalis LVVVAIHFPKQFDPATHKAL DKFLVSVSNVLTSKYR
Zebrafish IVVIAMLFPADFTPEVHVSV DKFFNNLALALSEKYR
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Hb Fukutomi [alpha 126(H9)Asp----Val]: a new hemoglobin variant with high oxygen affinity.
Hidaka K.; Iuchi I.; Kobayashi T.; Katoh K.; Yaguchi K.;
Cited for: VARIANT FUKUTOMI VAL-127;
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