Sequence information
Variant position: 392 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 412 The length of the canonical sequence.
Location on the sequence:
QESQGNTGLPDVELLSHELK
G VCPEPPGLDDPLAQDGAGVS
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human QESQGNTGLPDVELLSHELKG VCPEPPGLDDPLAQDGAGVS---------
PESHGDMGLPDVELLSHELKG ACPESPGLEGPLAQDGAGVS
Mouse QGSPG-----DVELLTQE-HQ EGQEHPGLGDHLAQGRVGTA
Rat QGSPR-----DVELPTQE-RQ EGQEHPGLRGHLVQARVGAS
Horse RESPGDTGLPDVELLSHELHG ASPESPGLEGPLAQDGAGVS
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
1 – 412
Adenosine receptor A2a
Topological domain
291 – 412
Cytoplasmic
Region
391 – 412
Disordered
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.