Variant position: 7 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 90 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human MPKRKA EGDAKGDKAKVKDEPQRRSAR
Mouse MPKRKA EGDAKGDKTKVKDEPQRRSAR
Rat MPKRNA EGDAKGDKAKVKDEPQRRSAR
Pig MPKRKA EGDAKGDKAKVKDEPQRRSAR
Bovine MPKRKA EGDAEGDKAKVKDEPQRRSAR
Chicken MPKRKA EGDTKGDKAKVKDEPQRRSAR
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 1 Removed
2 – 90 Non-histone chromosomal protein HMG-17
1 – 90 Disordered
1 – 26 Basic and acidic residues
25 – 25 Phosphoserine
Comparison of multiple forms of the high mobility group I proteins in rodent and human cells. Identification of the human high mobility group I-C protein.
Giancotti V.; Bandiera A.; Buratti E.; Fusco A.; Marzari R.; Coles B.; Goodwin G.H.;
Eur. J. Biochem. 198:211-216(1991)
Cited for: PROTEIN SEQUENCE OF 2-28; VARIANT LYS-7;
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