Variant position: 4032 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 4303 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human WSVFGKTLCRALPELLGVTL GLVVLGVAYAQLAILLVSSCV
Mouse WSVFGKTLCRALPELMGATL GLVLLGVAYAQMAILLISSGA
Caenorhabditis elegans IGVLAATLDNALGAIVSFGI AFLFFSMTFNSVLYAVLGNKM
Slime mold NQLFNQTLQQ---------- ---------------------
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Novel and recurrent mutations in the PKD1 (polycystic kidney disease) gene.
Daniells C.; Maheshwar M.M.; Lazarou L.; Davies F.; Coles G.; Ravine D.;
Hum. Genet. 102:216-220(1998)
Cited for: VARIANT PKD1 ASP-4032; VARIANT VAL-4045;
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