Variant position: 79 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 409 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VMIFVGFGFLMTFLKKYGFS SVGINLLVAALGLQWGTIVQG
Mouse VMIFVGFGFLMTFLKKYGFS GVGFNLFLAALGLQWGTIMQG
Rat VMIFVGFGFLMTFLKKYGFS GVGFNLFLAALGLQWGTIVQG
Bovine IMVFAGFGFLMTFLWKYGFS GVGINLLIAALGLQWGTIIQG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 409 Ammonium transporter Rh type A
73 – 79 Cytoplasmic
Candidate gene acting as a suppressor of the RH locus in most cases of Rh-deficiency.
Cherif-Zahar B.; Raynal V.; Gane P.; Mattei M.-G.; Bailly P.; Gibbs B.; Colin Y.; Cartron J.-P.;
Nat. Genet. 12:168-173(1996)
Cited for: VARIANT RHN ASN-79;
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.