Variant position: 325 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 560 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human PARASAPRLALDPDALAGFP QGLVNLSDPAALERLLDGEEP
Mouse LTQASNTQLALDPGALASFP QGLVNLSDPAALGRLLDWEEP
Rat LTRASNTRLALDPGALASFP QGLVNLSDPVALGRLLDGEEP
Pig PARIPPPSLALDPGALAGFP QGQVNLSDPAALERLLNSEEP
Bovine PARASPPRLALDPGALAGFP QGQVNLSDPAALERLLDGEEP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
26 – 560 Muellerian-inhibiting factor
329 – 329 N-linked (GlcNAc...) asparagine
Variants of the anti-Mullerian hormone gene in a compound heterozygote with the persistent Mullerian duct syndrome and his family.
Carre-Eusebe D.; Imbeaud S.; Harbison M.; New M.I.; Josso N.; Picard J.-Y.;
Hum. Genet. 90:389-394(1992)
Cited for: VARIANT ARG-325;
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