Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P00414: Variant p.His3Arg

Cytochrome c oxidase subunit 3
Gene: MT-CO3
Feedback?
Variant information Variant position: help 3
Type of variant: help LB/B
Residue change: help From Histidine (H) to Arginine (R) at position 3 (H3R, p.His3Arg).
Physico-chemical properties: help Change from medium size and polar (H) to large size and basic (R)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 3
Protein sequence length: help 261
Location on the sequence: help MT H QSHAYHMVKPSPWPLTGALS
Residue conservation: help 
Human                         MTHQSHAYHMVKPSPWPLTGALS

Gorilla                       MIHQSHAYHMVKPSPWPLTGALS

                              MTHQTHAYHMVNPSPWPLTGALS

Chimpanzee                    MTHQSHAYHMVKPSPWPLTGALS

Mouse                         MTHQTHAYHMVNPSPWPLTGAFS

Rat                           MTHQTHAYHMVNPSPWPLTGALS

Pig                           MTHQTHAYHMVNPSPWPLTGALS

Bovine                        MTHQTHAYHMVNPSPWPLTGALS

Rabbit                        MTHQTHAYHMVNPSPWPLTGALS

Sheep                         MTHQTHAYHMVNPSPWPLTGALS

Cat                           MTHQTHAYHMVNPSPWPLTGALS

Horse                         MTHQTHAYHMVNPSPWPLTGALS

Chicken                       MAHQAHSYHMVDPSPWPIFGAAA

Xenopus laevis                MAHQAHAYHMVDPSPWPLTGAVA

Zebrafish                     MAHQAHAYHMVDPSPWPLTGAVA

Caenorhabditis elegans        ---MFHNFHILSLSSYAYNLFFA

Drosophila                    STHSNHPFHLVDYSPWPLTGAIG

Slime mold                    KHMKRHPFHIVRGTVAPLAVTLP

Baker's yeast                 SRHQQHPFHMVMPSPWPIVVSFA

Fission yeast                 TKFQGHPYHIVSASPWPFFLSVV
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 261 Cytochrome c oxidase subunit 3
Topological domain 1 – 15 Mitochondrial matrix



Literature citations
Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome.
Rieder M.J.; Taylor S.L.; Tobe V.O.; Nickerson D.A.;
Nucleic Acids Res. 26:967-973(1998)
Cited for: VARIANTS ARG-3 AND SER-35;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.