Sequence information
Variant position: 186 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1042 The length of the canonical sequence.
Location on the sequence:
TSIKSTTLRVDQSILTGESV
S VIKHTDPVPDPRAVNQDKKN
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Mouse TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Rat TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Pig TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Rabbit TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Cat TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Chicken TSIKSTTLRVDQSILTGESVS VIKHTDPVPDPRAVNQDKKN
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
1 – 1042
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Topological domain
111 – 253
Cytoplasmic
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.