Variant position: 310 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1042 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Mouse RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Rat RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Pig RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Rabbit RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Cat RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Chicken RGAIYYFKIAVALAVAAIPE GLPAVITTCLALGTRRMAKKN
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 1042 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
296 – 313 Helical; Name=4
304 – 304 Calcium 1; via carbonyl oxygen
305 – 305 Calcium 1; via carbonyl oxygen
307 – 307 Calcium 1; via carbonyl oxygen
309 – 309 Calcium 1
294 – 294 3'-nitrotyrosine
295 – 295 3'-nitrotyrosine
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.