Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P00747: Variant p.Ile46Arg

Plasminogen
Gene: PLG
Feedback?
Variant information Variant position: help 46
Type of variant: help LB/B
Residue change: help From Isoleucine (I) to Arginine (R) at position 46 (I46R, p.Ile46Arg).
Physico-chemical properties: help Change from medium size and hydrophobic (I) to large size and basic (R)
BLOSUM score: help -3
Other resources: help


Sequence information Variant position: help 46
Protein sequence length: help 810
Location on the sequence: help VNTQGASLFSVTKKQLGAGS I EECAAKCEEDEEFTCRAFQY
Residue conservation: help 
Human                         VNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQY

Rhesus macaque                VNTKGASLFSITKKQLGAGSIEECAAKCEEEEEFTCRSFQY

Mouse                         ISTQGASLFSLTKKQLAAGGVSDCLAKCEGETDFVCRSFQY

Rat                           VSTQGASLHSLTKKQLAAGSIADCLAKCEGETDFICRSFQY

Pig                           VNTQGAFLFSLSRKQVAARSVEECAAKCEAETNFICRAFQY

Bovine                        VNTQGASLLSLSRKNLAGRSVEDCAAKCEEETDFVCRAFQY
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 20 – 810 Plasminogen
Chain 20 – 580 Plasmin heavy chain A
Peptide 20 – 97 Activation peptide
Domain 20 – 98 PAN
Helix 46 – 55



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.