Variant position: 309 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 511 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human DGGLQNMELHGMIMLRISDD KYGRIRLHVENEDK---KGVQLQT
Mouse DGGLQNMELHGMIMLRISDD KFGRIRLHVENEDK---KGVQ
Rat DGGLQNMELHGMIMLRISDD KFGRIRLHVENEDK---KGVQ
Bovine DGGLQNMELHGMIMLRISDD KFGRIRLHVENEDK---KGVQ
Chicken DGGLQNMELHGMIMLHISDE KFARIRLHVENEDK---RGVQ
Caenorhabditis elegans DGGLESGEVQATVTLSIGSP EFIPISIKMNNGSA---AGTQ
Slime mold DGTVESIDIKGGLSVQINDQ SLGKVKVNLKQGKLS--KQFQ
Baker's yeast DGTIHSSELKGVLELRINDH DLSHSNLKLADSIDVRDKSFQ
Fission yeast -------------------- ------------------AYE
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 511 Coatomer subunit delta
271 – 511 MHD
309 – 309 N6-acetyllysine
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.