Variant position: 206 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 759 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human TLSVLVGLFQVGLGLIHFGF VVTYLSEPLVRGYTTAAAVQV
Mouse TLSFLVGLFQVGLGLVHFGF VVTYLSEPLVRSYTTAASVQV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 759 Solute carrier family 26 member 6
187 – 207 Helical
145 – 216 GTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVR -> ATPGPLPLLTAPGRPTGGAGPDPLRLRGHLPVRTSCPRLYHSCSCAGLRLTAQVCVWPPSEQPLWATVPHLL. In isoform 7.
Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family.
Waldegger S.; Moschen I.; Ramirez A.; Smith R.J.H.; Ayadi H.; Lang F.; Kubisch C.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); TISSUE SPECIFICITY; SUBCELLULAR LOCATION; VARIANT MET-206;
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