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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P02768: Variant p.Lys383Asn

Albumin
Gene: ALB
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Variant information Variant position: help 383
Type of variant: help LB/B
Residue change: help From Lysine (K) to Asparagine (N) at position 383 (K383N, p.Lys383Asn).
Physico-chemical properties: help Change from large size and basic (K) to medium size and polar (N)
BLOSUM score: help 0
Polymorphism: help A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A.
Variant description: help In Trieste.
Other resources: help


Sequence information Variant position: help 383
Protein sequence length: help 609
Location on the sequence: help PDYSVVLLLRLAKTYETTLE K CCAAADPHECYAKVFDEFKP
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 25 – 609 Albumin
Domain 211 – 403 Albumin 2
Site 383 – 383 Not glycated
Site 396 – 396 Not glycated
Glycosylation 375 – 375 N-linked (Glc) (glycation) lysine
Glycosylation 402 – 402 N-linked (Glc) (glycation) lysine; in vitro
Disulfide bond 340 – 385
Helix 367 – 384



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.