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UniProtKB/Swiss-Prot Q15047: Variant p.Asn236Ser

Histone-lysine N-methyltransferase SETDB1
Gene: SETDB1
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Variant information Variant position: help 236
Type of variant: help LB/B
Residue change: help From Asparagine (N) to Serine (S) at position 236 (N236S, p.Asn236Ser).
Physico-chemical properties: help Change from medium size and polar (N) to small size and polar (S)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 236
Protein sequence length: help 1291
Location on the sequence: help GTLIAIQTVGPGKKYKVKFD N KGKSLLSGNHIAYDYHPPAD
Residue conservation: help 
Human                         GTLIAIQTV----------GPGKKYKVKFDNKGKSLL---SGNHIAYDYHPPAD

Mouse                         GTLIAIQTV----------GLGKKYKVKFDNKGKSLL---S

Xenopus laevis                GTLISIQCV----------GTGKKFKVKFDNKGKSLL---S

Drosophila                    ASWVSIKVIEFTESTAINGNTMKSYKIRYLNTPYQMIKTVT
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1291 Histone-lysine N-methyltransferase SETDB1
Beta strand 227 – 237



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.