Sequence information
Variant position: 331 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 509 The length of the canonical sequence.
Location on the sequence:
VCIGRRPFTKNLGLEELGIE
L DPRGRIPVNTRFQTKIPNIY
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VCIGRRPFTKNLGLEELGIEL DPRGRIPVNTRFQTKIPNIY
VCIGRRPFTQNLGLEELGIEL DPRGRIPVNTRFQTKIPNIY
Mouse VCIGRRPFTQNLGLEELGIEL DPKGRIPVNNRFQTKIPNIY
Rat VCIGRRPFTQNLGLEELGIEL DPKGRIPVNTRFQTKIPNIF
Pig VCIGRRPFTQNLGLEELGIEL DPRGRIPVNTRFQTKIPNIY
Caenorhabditis elegans VSVGRRPYTEGLGLSNVQIDL DNRGRVPVNERFQTKVPSIF
Slime mold VSVGRRPNTSGLGLESVGIPT DKAGRVEVGDHFNTKVPSIF
Baker's yeast VAVGRRPYIAGLGAEKIGLEV DKRGRLVIDDQFNSKFPHIK
Fission yeast VAIGRVPYTEGLGLDKLGISM DKSNRVIMDSEYRTNIPHIR
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
36 – 509
Dihydrolipoyl dehydrogenase, mitochondrial
Binding site
314 – 314
Modified residue
346 – 346
N6-acetyllysine
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.