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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P01583: Variant p.Asp176His

Interleukin-1 alpha
Gene: IL1A
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Variant information Variant position: help 176
Type of variant: help LB/B
Residue change: help From Aspartate (D) to Histidine (H) at position 176 (D176H, p.Asp176His).
Physico-chemical properties: help Change from medium size and acidic (D) to medium size and polar (H)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 176
Protein sequence length: help 271
Location on the sequence: help ALHNLDEAVKFDMGAYKSSK D DAKITVILRISKTQLYVTAQ
Residue conservation: help 
Human                         ALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQ

                              ALQNLDDAVKFDMGAYT--SEDSKLPVTLRISKTRLFVSAQ

Rhesus macaque                AIHNLDEAVKFDMGAYTSSKDDTKVPVILRISKTQLYVSAQ

Mouse                         WLNDLQQEVKFDMYAYSSGGDDSKYPVTLKISDSQLFVSAQ

Rat                           SLNDLQLEVKFDMYAYSSGGDDSKYPVTLKVSNTQLFVSAQ

Pig                           VLNNLDEAVKFDMAAYT-SNDDSQLPVTLRISETRLFVSAQ

Bovine                        TLNNLEEAVKFDMVAYV-SEEDSQLPVTLRISKTQLFVSAQ

Rabbit                        PLQNLGDAVKFDMGVYM-TSEDSILPVTLRISQTPLFVSAQ

Goat                          TLNNLEEAVKFDMVAYV-SEEDSQLPVTLRISKTQLFVSAQ

Sheep                         TLNNLEEAVKFDMVAYV-SEEDSQLPVTLRISKTQLFVSAQ

Cat                           ALQNLDDAVKFDMGAYT-SKEDSKLPVTLRISKTRLFVSAQ

Horse                         ALNNLDDAVKFDMGAYT-SEEDSQLPVTLRISKTRLFVSAQ
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 113 – 271 Interleukin-1 alpha
Beta strand 176 – 178



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.