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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P21731: Variant p.Val176Glu

Thromboxane A2 receptor
Gene: TBXA2R
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Variant information Variant position: help 176
Type of variant: help LB/B
Residue change: help From Valine (V) to Glutamate (E) at position 176 (V176E, p.Val176Glu).
Physico-chemical properties: help Change from medium size and hydrophobic (V) to medium size and acidic (E)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 176
Protein sequence length: help 343
Location on the sequence: help VWAAALALGLLPLLGVGRYT V QYPGSWCFLTLGAESGDVAF
Residue conservation: help 
Human                         VWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAF

Mouse                         VWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVF

Rat                           VWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAF

Bovine                        VWASALALGLLPLLGVGHYTVQYPGSWCFLTLGTDPGDVAF
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 343 Thromboxane A2 receptor
Topological domain 173 – 193 Extracellular
Disulfide bond 105 – 183
Beta strand 174 – 176



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.